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Clinical trials.
Research Starter

Clinical trials.

  • Clinical trials offer the most reliable process for bringing new drugs and medical treatments into public use. The process has ... More
  • Magill’s Medical Guide (Online Edition), 2020. 2p.
Academic Journal

Data Monitoring for the Chinese Clinical Trials of Remdesivir in Treating Patients with COVID-19 During the Pandemic Crisis.

  • Authors : Shih WJ; Rutgers University School of Public Health, Piscataway, NJ, USA. .; Yao C

Subjects: Clinical Trials, Phase III as Topic* ; Data Accuracy* ; Randomized Controlled Trials as Topic* COVID-19COVID-19 drug treatment...

  • Source: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2020 Sep; Vol. 54 (5), pp. 1236-1255. Date of Electronic Publication: 2020 May 16.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101597411 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Latent Dirichlet Allocation in predicting clinical trial terminations.

  • Authors : Geletta S; Department of Public Health, Des Moines University, 169 Ryan Hall, 3200 Grand Ave, Des Moines, IA, USA. .; Follett L

Subjects: Early Termination of Clinical Trials* ; Machine Learning* ; Models, Theoretical*

  • Source: BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2019 Nov 27; Vol. 19 (1), pp. 242. Date of Electronic Publication: 2019 Nov 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101088682 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6947

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Academic Journal

Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)--The BRACE CORONA Trial.

Subjects: Betacoronavirus* ; Pragmatic Clinical Trials as Topic*; Angiotensin Receptor Antagonists/Angiotensin Receptor Antagonists/Angiotensin Receptor Antagonists/*therapeutic use COVID-19severe acute respiratory syndrome coronavirus 2

  • Source: American heart journal [Am Heart J] 2020 Aug; Vol. 226, pp. 49-59. Date of Electronic Publication: 2020 May 13.Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744

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Academic Journal

Evaluation of long-term effectiveness of the use of carglumic acid in patients with propionic acidemia (PA) or methylmalonic acidemia (MMA): study protocol for a randomized controlled trial.

  • Authors : Nashabat M; Genetics Division, Department of Pediatrics, King Abdullah International Medical Research Centre, King Saud bin Abdulaziz University for Health Science, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (NGHA), PO Box 22490 11426, Riyadh, Saudi Arabia.; Obaid A

Subjects: Clinical Trials, Phase III as Topic* ; Randomized Controlled Trials as Topic*; Amino Acid Metabolism, Inborn Errors/Amino Acid Metabolism, Inborn Errors/Amino Acid Metabolism, Inborn Errors/*drug therapy Methylmalonic acidemia

  • Source: BMC pediatrics [BMC Pediatr] 2019 Jun 13; Vol. 19 (1), pp. 195. Date of Electronic Publication: 2019 Jun 13.Publisher: BioMed Central Country of Publication: England NLM ID: 100967804 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2431

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Academic Journal

Achieving effective informed oversight by DMCs in COVID clinical trials.

  • Authors : DeMets DL; University of Wisconsin-Madison, Madison, WI, USA. Electronic address: .; Fleming TR

Subjects: Betacoronavirus* ; Clinical Trials Data Monitoring Committees* ; Research Design*COVID-19severe acute respiratory syndrome coronavirus 2

  • Source: Journal of clinical epidemiology [J Clin Epidemiol] 2020 Oct; Vol. 126, pp. 167-171. Date of Electronic Publication: 2020 Jul 10.Publisher: Elsevier Country of Publication: United States NLM ID: 8801383 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy.

  • Authors : Addis A; Regional Health Service, Regione Lazio, Rome, Italy (A.A.).; Genazzani A

Subjects: Betacoronavirus* ; Clinical Trials as Topic* ; Disease Management* COVID-19severe acute respiratory syndrome coronavirus 2

  • Source: Annals of internal medicine [Ann Intern Med] 2020 Oct 20; Vol. 173 (8), pp. 654-655. Date of Electronic Publication: 2020 Jun 16.Publisher: American College of Physicians--American Society of Internal Medicine Country of Publication: United States NLM ID: 0372351 Publication Model:

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Editorial & Opinion

Moving fast but going slow: coordination challenges for trials of COVID-19 post-exposure prophylaxis.

  • Authors : Tan DHS; Division of Infectious Diseases, St. Michael's Hospital, 30 Bond St., Toronto, ON, M5B 1W8, Canada. .; MAP Centre for Urban Health Solutions, St. Michael's Hospital, 30 Bond St., Toronto, ON, M5B 1W8, Canada. .

Subjects: Clinical Trials as Topic* ; Post-Exposure Prophylaxis*; Antiviral Agents/Antiviral Agents/Antiviral Agents/*administration & dosage COVID-19severe acute respiratory syndrome coronavirus 2

  • Source: Trials [Trials] 2020 Sep 29; Vol. 21 (1), pp. 815. Date of Electronic Publication: 2020 Sep 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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Editorial & Opinion

It is unprecedented: trial management during the COVID-19 pandemic and beyond.

  • Authors : Mitchell EJ; Nottingham Clinical Trials Unit, University of Nottingham, Building 42, University Park, Nottingham, NG7 2RD, UK. .; Ahmed K

Subjects: Coronavirus Infections*/Coronavirus Infections*/Coronavirus Infections*/diagnosis ; Coronavirus Infections*/Coronavirus Infections*/Coronavirus Infections*/therapy ; Coronavirus Infections*/Coronavirus Infections*/Coronavirus Infections*/virology COVID-19severe acute respiratory syndrome coronavirus 2

  • Source: Trials [Trials] 2020 Sep 11; Vol. 21 (1), pp. 784. Date of Electronic Publication: 2020 Sep 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215

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Academic Journal

The next decade of clinical trials in locoregionally advanced nasopharyngeal carcinoma.

  • Authors : Peng L; Department of Radiation Oncology, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China

Subjects: Clinical Trials as Topic/Clinical Trials as Topic/Clinical Trials as Topic/*methods ; Nasopharyngeal Carcinoma/Nasopharyngeal Carcinoma/Nasopharyngeal Carcinoma/*therapy ; Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/Nasopharyngeal Neoplasms/*therapy

  • Source: The British journal of radiology [Br J Radiol] 2019 Oct; Vol. 92 (1102), pp. 20181031. Date of Electronic Publication: 2019 May 24.Publisher: British Institute of Radiology Country of Publication: England NLM ID: 0373125 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Construction and optimization of gene expression signatures for prediction of survival in two-arm clinical trials.

  • Authors : Theilhaber J; Sanofi Oncology, 270 Albany Street, Cambridge, MA, 02139, USA. .; Chiron M

Subjects: Clinical Trials as Topic* ; Gene Expression Profiling* ; Gene Expression Regulation, Neoplastic*

  • Source: BMC bioinformatics [BMC Bioinformatics] 2020 Jul 25; Vol. 21 (1), pp. 333. Date of Electronic Publication: 2020 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105

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