Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.

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  • Additional Information
    • Affiliation:
      Centre for Clinical Brain Sciences (H.Y.Y.C., A.J.C., M.S.D., G.E.M., W.N.W.), University of Edinburgh, UK.
      Centre for Medical Informatics, Usher Institute (A.T.), University of Edinburgh, UK.
      Royal Infirmary of Edinburgh (C.C.), National Health Service Lothian, Edinburgh, UK.
    • Abstract:
      Background and Purpose: Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized controlled trial workflow that enabled all trial procedures to be carried out remotely. In addition, we explored the feasibility of wrist-worn actigraphy sensor as a way of measuring objective outcomes in this clinical trial.Methods: We recruited adult community-based stroke patients (n=27) and randomly allocated them to TASK-CBT (n=14) or relaxation therapy (TASK-Relax), an active comparator (n=13).Results: In our sample (mean age 65 [±10]; 56% men; 63% stroke, 37% transient ischemic attacks), remote self-enrolment, electronic signature, intervention delivery, and automated follow-up were feasible. All participants completed all TASK-CBT sessions (14/14). Lower levels of anxiety were observed in TASK-CBT when compared with TASK-Relax at both weeks 6 and 20. Mean actigraphy sensor wearing-time was 33 days (±15).Conclusions: Our preliminary feasibility data from the current study support a larger definitive clinical trial and the use of wrist-worn actigraphy sensor in anxious stroke survivors. Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT03439813.
    • Journal Subset:
      Allied Health; Biomedical; Peer Reviewed; USA
    • ISSN:
      0039-2499
    • MEDLINE Info:
      PMID: NLM32576090 NLM UID: 0235266
    • Publication Date:
      In Process
    • Publication Date:
      20200807
    • DOI:
      10.1161/STROKEAHA.120.029042
    • Accession Number:
      144801663
  • Citations
    • ABNT:
      CHUN, H.-Y. Y. et al. Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial. Stroke (00392499), [s. l.], v. 51, n. 8, p. 2297–2306, 2020. DOI 10.1161/STROKEAHA.120.029042. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=144801663. Acesso em: 30 set. 2020.
    • AMA:
      Chun H-YY, Carson AJ, Tsanas A, et al. Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial. Stroke (00392499). 2020;51(8):2297-2306. doi:10.1161/STROKEAHA.120.029042
    • APA:
      Chun, H.-Y. Y., Carson, A. J., Tsanas, A., Dennis, M. S., Mead, G. E., Calabria, C., & Whiteley, W. N. (2020). Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial. Stroke (00392499), 51(8), 2297–2306. https://doi.org/10.1161/STROKEAHA.120.029042
    • Chicago/Turabian: Author-Date:
      Chun, Ho-Yan Yvonne, Alan J. Carson, Athanasios Tsanas, Martin S. Dennis, Gillian E. Mead, Clementina Calabria, and William N. Whiteley. 2020. “Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.” Stroke (00392499) 51 (8): 2297–2306. doi:10.1161/STROKEAHA.120.029042.
    • Harvard:
      Chun, H.-Y. Y. et al. (2020) ‘Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial’, Stroke (00392499), 51(8), pp. 2297–2306. doi: 10.1161/STROKEAHA.120.029042.
    • Harvard: Australian:
      Chun, H-YY, Carson, AJ, Tsanas, A, Dennis, MS, Mead, GE, Calabria, C & Whiteley, WN 2020, ‘Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial’, Stroke (00392499), vol. 51, no. 8, pp. 2297–2306, viewed 30 September 2020, .
    • MLA:
      Chun, Ho-Yan Yvonne, et al. “Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.” Stroke (00392499), vol. 51, no. 8, Aug. 2020, pp. 2297–2306. EBSCOhost, doi:10.1161/STROKEAHA.120.029042.
    • Chicago/Turabian: Humanities:
      Chun, Ho-Yan Yvonne, Alan J. Carson, Athanasios Tsanas, Martin S. Dennis, Gillian E. Mead, Clementina Calabria, and William N. Whiteley. “Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.” Stroke (00392499) 51, no. 8 (August 2020): 2297–2306. doi:10.1161/STROKEAHA.120.029042.
    • Vancouver/ICMJE:
      Chun H-YY, Carson AJ, Tsanas A, Dennis MS, Mead GE, Calabria C, et al. Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial. Stroke (00392499) [Internet]. 2020 Aug [cited 2020 Sep 30];51(8):2297–306. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=144801663