Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Additional Information
    • Affiliation:
      Department of Psychiatry and Neurology & Ophthalmology, Michigan State University, East Lansing, 909 Wilson Road, Rm 327, West Fee Road, 48824, East Lansing, MI, USA
      Department of Psychology, Indiana Wesleyan University, Marion, Indiana, USA
      Prowers Medical Center, Lamar, CO, USA
    • Abstract:
      Background: The universally adopted 2018 PCOS medical diagnostic and treatment guidelines for Polycystic Ovarian Syndrome (PCOS) cites the need for a brief screening measure that can be easily administered in the clinical care setting. We evaluate a 12-item questionnaire emphasizing the medical symptoms of PCOS with a group of women with PCOS as well as comparison samples of college women not diagnosed with PCOS.Method: Of 120 undergraduate psychology women 18 to 41 years of age, 86 screened negative on a 12-item PCOS symptoms inventory. They were compared to a group of PCOS patients diagnosed medically in a manner consistent with the Teede et al. (2018) evidence-based diagnostic guidelines. The screen-positive, screen-negative, and PCOS-confirmed groups were compared on the PCOS Quality-of-Life (QoL) questionnaire, Zung Self-Rating Depression Scale (ZDS), Spielberg State-Trait Anxiety Inventory (STAI), Fatigue Symptom Inventory (FSI), Spiritual well-being and Spiritual Beliefs Inventories, the computerized Automated Neuropsychological Assessment Metric (ANAM) battery, and an experimental tachistoscopic Bilateral Perceptual Asymmetries Letter and Dots Matching Bilateral Field Advantage (BFA) test (to evaluate the effects of early brain androgenization possible from PCOS). For each questionnaire and neuropsychological performance principal outcome, the Linear Mixed Effects (LME) model was employed to evaluate the predictive significance of demographic characteristics and group membership (confirmed cases, screen negative and screen positive cases) for these outcomes.Results: The PCOS-confirmed women scored more poorly than the screen-negative (reference) and screen-positive groups on all the measures of physical, emotional, social, and spiritual well-being measures. On the ANAM neuropsychological battery, PCOS-confirmed women did more poorly on Sternberg Memory and Stimulus Response throughput measures. They also had slower correct response speed for both the unilateral and bilateral dot- and letter-matching tachistoscopic stimulus presentations. However, the bilateral field advantage throughput performance ratio did not differ among groups, which is a global measure of bilateral versus unilateral brain/behavior asymmetries.Conclusion: PCOS screening can be a feasible and important part of women's healthcare. PCOS-confirmed women should receive not only the medical standard of care from the 2018 guidelines, but also comprehensive psychosocial and neurocognitive support to enhance their quality of life.
    • Journal Subset:
      Biomedical; Europe; UK & Ireland
    • ISSN:
      1472-6874
    • MEDLINE Info:
      PMID: NLM32576264 NLM UID: 101088690
    • Publication Date:
      In Process
    • Publication Date:
      20200627
    • DOI:
      http://dx.doi.org/10.1186/s12905-020-00994-8
    • Accession Number:
      144202044
  • Citations
    • ABNT:
      BOIVIN, M. J. et al. Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation. BMC Women’s Health, [s. l.], v. 20, n. 1, p. 1–12, 2020. DOI 10.1186/s12905-020-00994-8. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=144202044. Acesso em: 18 set. 2020.
    • AMA:
      Boivin MJ, Fatehi F, Phillips-Chan AE, Richardson JR, Summers AN, Foley SA. Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation. BMC Women’s Health. 2020;20(1):1-12. doi:10.1186/s12905-020-00994-8
    • APA:
      Boivin, M. J., Fatehi, F., Phillips-Chan, A. E., Richardson, J. R., Summers, A. N., & Foley, S. A. (2020). Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation. BMC Women’s Health, 20(1), 1–12. https://doi.org/10.1186/s12905-020-00994-8
    • Chicago/Turabian: Author-Date:
      Boivin, Michael J., Farnaz Fatehi, Amy E. Phillips-Chan, Julia R. Richardson, Amanda N. Summers, and Steven A. Foley. 2020. “Exploratory Study of a Screening Measure for Polycystic Ovarian Syndrome, Quality of Life Assessment, and Neuropsychological Evaluation.” BMC Women’s Health 20 (1): 1–12. doi:10.1186/s12905-020-00994-8.
    • Harvard:
      Boivin, M. J. et al. (2020) ‘Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation’, BMC Women’s Health, 20(1), pp. 1–12. doi: 10.1186/s12905-020-00994-8.
    • Harvard: Australian:
      Boivin, MJ, Fatehi, F, Phillips-Chan, AE, Richardson, JR, Summers, AN & Foley, SA 2020, ‘Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation’, BMC Women’s Health, vol. 20, no. 1, pp. 1–12, viewed 18 September 2020, .
    • MLA:
      Boivin, Michael J., et al. “Exploratory Study of a Screening Measure for Polycystic Ovarian Syndrome, Quality of Life Assessment, and Neuropsychological Evaluation.” BMC Women’s Health, vol. 20, no. 1, June 2020, pp. 1–12. EBSCOhost, doi:10.1186/s12905-020-00994-8.
    • Chicago/Turabian: Humanities:
      Boivin, Michael J., Farnaz Fatehi, Amy E. Phillips-Chan, Julia R. Richardson, Amanda N. Summers, and Steven A. Foley. “Exploratory Study of a Screening Measure for Polycystic Ovarian Syndrome, Quality of Life Assessment, and Neuropsychological Evaluation.” BMC Women’s Health 20, no. 1 (June 23, 2020): 1–12. doi:10.1186/s12905-020-00994-8.
    • Vancouver/ICMJE:
      Boivin MJ, Fatehi F, Phillips-Chan AE, Richardson JR, Summers AN, Foley SA. Exploratory study of a screening measure for polycystic ovarian syndrome, quality of life assessment, and neuropsychological evaluation. BMC Women’s Health [Internet]. 2020 Jun 23 [cited 2020 Sep 18];20(1):1–12. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=144202044