Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster.

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  • Author(s): Hsieh, Shu-Ling; Tsai, Pi-Jen; Liu, Ya-Ching; Wu, Chih-Chung
  • Source:
    Evidence-based Complementary & Alternative Medicine (eCAM) (EVID BASED COMPLEMENT ALTERN MED), 6/10/2020; 1-11. (11p)
  • Publication Type:
    Article - pictorial, research, tables/charts
  • Language:
    English
  • Additional Information
    • Affiliation:
      Department of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung 81157, Taiwan
      Department of Food Science, National Pingtung University of Technology and Science, Pingtung 91207, Taiwan
      Department of Food and Nutrition, Providence University, Taichung 43301, Taiwan
    • Subject Terms:
    • Subject Terms:
    • Abstract:
      Gynura bicolor (Roxb. and Willd.) DC (G. bicolor) is a dietary vegetable in the Far East. The aims of the present study were to investigate the antioxidant effects of the G. bicolor water extract (GBWE) and its ability to regulate the blood lipid and lipoprotein profiles. In this study, the pigment composition and antioxidant ability of the GBWE were analyzed. Syrian hamsters were fed a high-fat diet (HFD) and the GBWE for 12 weeks, and the blood lipid levels, lipoprotein profiles, and cholesterol metabolism-related enzyme levels were then examined. The results showed that the GBWE exhibited excellent 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity and ferrous-ion-chelating ability. The hepatic glutathione levels in the hamsters were increased after the administration of low (0.4 g/kg BW, GBWE-L) or high (0.8 g/kg BW, GBWE-H) levels of the GBWE. The GBWE-H-treated hamsters exhibited significantly decreased serum levels of total cholesterols (TC) and low-density lipoprotein-cholesterol (LDL-C) and significantly increased levels of lectin-cholesterol acetyltransferase (LCAT). These results showed that GBWE-H can reduce the total cholesterol and LDL-C levels in HFD-fed hamsters, and this reduction might be involved in the regulation of LCAT expression.
    • Journal Subset:
      Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland
    • ISSN:
      1741-427X
    • MEDLINE Info:
      NLM UID: 101215021
    • Publication Date:
      20200613
    • Publication Date:
      20200615
    • DOI:
      10.1155/2020/2907610
    • Accession Number:
      143705743
  • Citations
    • ABNT:
      HSIEH, S.-L. et al. Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster. Evidence-based Complementary & Alternative Medicine (eCAM), [s. l.], p. 1–11, 2020. DOI 10.1155/2020/2907610. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=143705743. Acesso em: 25 set. 2020.
    • AMA:
      Hsieh S-L, Tsai P-J, Liu Y-C, Wu C-C. Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster. Evidence-based Complementary & Alternative Medicine (eCAM). June 2020:1-11. doi:10.1155/2020/2907610
    • APA:
      Hsieh, S.-L., Tsai, P.-J., Liu, Y.-C., & Wu, C.-C. (2020). Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster. Evidence-Based Complementary & Alternative Medicine (ECAM), 1–11. https://doi.org/10.1155/2020/2907610
    • Chicago/Turabian: Author-Date:
      Hsieh, Shu-Ling, Pi-Jen Tsai, Ya-Ching Liu, and Chih-Chung Wu. 2020. “Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura Bicolor Water Extracts in Syrian Hamster.” Evidence-Based Complementary & Alternative Medicine (ECAM), June, 1–11. doi:10.1155/2020/2907610.
    • Harvard:
      Hsieh, S.-L. et al. (2020) ‘Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster’, Evidence-based Complementary & Alternative Medicine (eCAM), pp. 1–11. doi: 10.1155/2020/2907610.
    • Harvard: Australian:
      Hsieh, S-L, Tsai, P-J, Liu, Y-C & Wu, C-C 2020, ‘Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster’, Evidence-based Complementary & Alternative Medicine (eCAM), pp. 1–11, viewed 25 September 2020, .
    • MLA:
      Hsieh, Shu-Ling, et al. “Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura Bicolor Water Extracts in Syrian Hamster.” Evidence-Based Complementary & Alternative Medicine (ECAM), June 2020, pp. 1–11. EBSCOhost, doi:10.1155/2020/2907610.
    • Chicago/Turabian: Humanities:
      Hsieh, Shu-Ling, Pi-Jen Tsai, Ya-Ching Liu, and Chih-Chung Wu. “Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura Bicolor Water Extracts in Syrian Hamster.” Evidence-Based Complementary & Alternative Medicine (ECAM), June 10, 2020, 1–11. doi:10.1155/2020/2907610.
    • Vancouver/ICMJE:
      Hsieh S-L, Tsai P-J, Liu Y-C, Wu C-C. Potential Effects of Antioxidant and Serum Cholesterol-Lowering Effects of Gynura bicolor Water Extracts in Syrian Hamster. Evidence-based Complementary & Alternative Medicine (eCAM) [Internet]. 2020 Jun 10 [cited 2020 Sep 25];1–11. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=143705743