Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019).

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  • Additional Information
    • Affiliation:
      Laboratory of Bacterial Pathogenesis and Immunology, Rockefeller University, 1230 York Avenue, New York, NY, USA
      Central European Institute of Technology (CEITEC), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic
      Northern Ireland Centre for Stratified Medicine, School of Biomedical Sciences, Ulster University, Londonderry, UK
      Department of Orthopedics, Physical Medicine and Rehabilitation, University of Munich (LMU), Munich, Germany
      Marian University Osteopathic Medical School, Indianapolis, IN, USA
      Celgene Corporation, Information Knowledge and Utilization, San Francisco, CA, USA
    • Subject Terms:
    • Subject Terms:
    • Abstract:
      Such observations are practically impossible to explain by contamination as this would require the contaminant to form a biofilm deep within a retrieved nucleus tissue fragment during the brief time between removal and freezing. Critically, there is no indication that biopsy samples were processed by homogenization to vigorously disrupt any I C. acnes i biofilm matrix residing deep within the disc tissue sample, thus enhancing culture detection and minimizing false-negative results [[4]]. We believe that the best methodological approach for future studies investigating the role of I C. acnes i in DDD is to utilize disc tissue homogenization combined with imaging techniques that are sensitive to the presence of biofilms, but eliminate the issue of contamination.
    • Journal Subset:
      Biomedical; Continental Europe; Europe; Peer Reviewed
    • Instrumentation:
      Diagnostic Interview Schedule for Children (DISC)
      Behavior Rating Inventory of Executive Function (BRIEF)
    • ISSN:
      0940-6719
    • MEDLINE Info:
      PMID: NLM31797137 NLM UID: 9301980
    • Publication Date:
      20201030
    • Publication Date:
      20201030
    • DOI:
      10.1007/s00586-019-06237-1
    • Accession Number:
      142164826
  • Citations
    • ABNT:
      CAPOOR, M. N. et al. Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019). European Spine Journal, [s. l.], v. 29, n. 3, p. 628–630, 2020. DOI 10.1007/s00586-019-06237-1. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=142164826. Acesso em: 6 dez. 2020.
    • AMA:
      Capoor MN, McDowell A, Birkenmaier C, et al. Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019). European Spine Journal. 2020;29(3):628-630. doi:10.1007/s00586-019-06237-1
    • APA:
      Capoor, M. N., McDowell, A., Birkenmaier, C., Ahmed, F. S., Coscia, E., Raz, A., Mavrommatis, K., Fischetti, V. A., & Slaby, O. (2020). Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019). European Spine Journal, 29(3), 628–630. https://doi.org/10.1007/s00586-019-06237-1
    • Chicago/Turabian: Author-Date:
      Capoor, Manu N., Andrew McDowell, Christof Birkenmaier, Fahad S. Ahmed, Erin Coscia, Assaf Raz, Konstantinos Mavrommatis, Vincent A. Fischetti, and Ondrej Slaby. 2020. “Letter to the Editor Concerning ‘Bacteria: Back Pain, Leg Pain and Modic Sign: A Surgical Multicenter Comparative Study’ by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et Al. Eur Spine J (2019).” European Spine Journal 29 (3): 628–30. doi:10.1007/s00586-019-06237-1.
    • Harvard:
      Capoor, M. N. et al. (2020) ‘Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019)’, European Spine Journal, 29(3), pp. 628–630. doi: 10.1007/s00586-019-06237-1.
    • Harvard: Australian:
      Capoor, MN, McDowell, A, Birkenmaier, C, Ahmed, FS, Coscia, E, Raz, A, Mavrommatis, K, Fischetti, VA & Slaby, O 2020, ‘Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019)’, European Spine Journal, vol. 29, no. 3, pp. 628–630, viewed 6 December 2020, .
    • MLA:
      Capoor, Manu N., et al. “Letter to the Editor Concerning ‘Bacteria: Back Pain, Leg Pain and Modic Sign: A Surgical Multicenter Comparative Study’ by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et Al. Eur Spine J (2019).” European Spine Journal, vol. 29, no. 3, Mar. 2020, pp. 628–630. EBSCOhost, doi:10.1007/s00586-019-06237-1.
    • Chicago/Turabian: Humanities:
      Capoor, Manu N., Andrew McDowell, Christof Birkenmaier, Fahad S. Ahmed, Erin Coscia, Assaf Raz, Konstantinos Mavrommatis, Vincent A. Fischetti, and Ondrej Slaby. “Letter to the Editor Concerning ‘Bacteria: Back Pain, Leg Pain and Modic Sign: A Surgical Multicenter Comparative Study’ by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et Al. Eur Spine J (2019).” European Spine Journal 29, no. 3 (March 2020): 628–30. doi:10.1007/s00586-019-06237-1.
    • Vancouver/ICMJE:
      Capoor MN, McDowell A, Birkenmaier C, Ahmed FS, Coscia E, Raz A, et al. Letter to the Editor concerning “Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study” by Fritzell, P., Welinder-Olsson, C., Jönsson, B. et al. Eur Spine J (2019). European Spine Journal [Internet]. 2020 Mar [cited 2020 Dec 6];29(3):628–30. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=rzh&AN=142164826