Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men

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  • Source:
    Contemporary clinical trials 2015 45 Pt B, 244 (244-251) Published by: Elsevier Inc. United States
  • Additional Information
    • Author(s):
      Garcia J, Colson PW, Parker C, Hirsch JS
    • Contact Information:
      J. Garcia, College of Public Health and Human Sciences, Oregon State University, 118C Milam Hall, 2520 SW Campus Way, Corvallis, OR 97331, United States. E-mail: jonathan.garcia@oregonstate.edu
    • Language:
      English
    • Publication Type:
      Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
    • Record Status:
      This record is updated this issue.
    • Abstract:
      Although HIV interventions and clinical trials increasingly report the use of mixed methods, studies have not reported on the process through which ethnographic or qualitative findings are incorporated into RCT designs. We conducted a community-based ethnography on social and structural factors that may affect the acceptance of and adherence to oral pre-exposure prophylaxis (PrEP) among Black men who have sex with men (BMSM). We then devised the treatment arm of an adherence clinical trial drawing on findings from the community-based ethnography. This article describes how ethnographic findings informed the RCT and identifies distilled themes and findings that could be included as part of an RCT. The enhanced intervention includes in-person support groups, online support groups, peer navigation, and text message reminders. By describing key process-related facilitators and barriers to conducting meaningful mixed methods research, we provide important insights for the practice of designing clinical trials for 'real-world' community settings.
    • EMBASE keywords:
      article; Black person; casual sex; condom use; controlled study; ethnographic research; *ethnography; homosexuality; human; *Human immunodeficiency virus infection/pc [Prevention]; intervention study; male; medication compliance; *men who have sex with men; patient compliance; patient education; peer group; post exposure prophylaxis; *pre exposure prophylaxis; randomized controlled trial; self actualization; sexual behavior; social acceptance; social class; social environment; social status; study design; support group
      Humans
      Male
      Acquired Immunodeficiency Syndrome/prevention & control
      African Americans
      Anthropology, Cultural
      Health Knowledge, Attitudes, Practice
      Homosexuality, Male
      Patient Acceptance of Health Care
      Reminder Systems
      Research Design
      Self-Help Groups
      Social Networking
      Anti-HIV Agents/*administration & dosage
      HIV Infections/*prevention & control
      Medication Adherence/*psychology
      Pre-Exposure Prophylaxis/*methods
    • Accession Number:
      606787074
    • Source:
      This document should be cited as: Garcia J Colson PW Parker C Hirsch JS. Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men 2015 (The Cochrane Controlled Trials Register (CCTR/CENTRAL). DOI: 10.1016/j.cct.2015.10.005. Oxford: Update Software. Updated quarterly.
    • Accession Number:
      CN-01104795
  • Citations
    • ABNT:
      GARCIA J et al. Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men. Contemporary clinical trials, [s. l.], v. 45, n. Pt B, p. 244–251, 2015. DOI 10.1016/j.cct.2015.10.005. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cgh&AN=CN-01104795. Acesso em: 9 ago. 2020.
    • AMA:
      Garcia J, Colson PW, Parker C, Hirsch JS. Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men. Contemporary clinical trials. 2015;45(Pt B):244-251. doi:10.1016/j.cct.2015.10.005
    • APA:
      Garcia J, Colson PW, Parker C, & Hirsch JS. (2015). Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men. Contemporary Clinical Trials, 45(Pt B), 244–251. https://doi.org/10.1016/j.cct.2015.10.005
    • Chicago/Turabian: Author-Date:
      Garcia J, Colson PW, Parker C, and Hirsch JS. 2015. “Passing the Baton: Community-Based Ethnography to Design a Randomized Clinical Trial on the Effectiveness of Oral Pre-Exposure Prophylaxis for HIV Prevention among Black Men Who Have Sex with Men.” Contemporary Clinical Trials 45 (Pt B): 244–51. doi:10.1016/j.cct.2015.10.005.
    • Harvard:
      Garcia J et al. (2015) ‘Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men’, Contemporary clinical trials, 45(Pt B), pp. 244–251. doi: 10.1016/j.cct.2015.10.005.
    • Harvard: Australian:
      Garcia J, Colson PW, Parker C & Hirsch JS 2015, ‘Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men’, Contemporary clinical trials, vol. 45, no. Pt B, pp. 244–251, viewed 9 August 2020, .
    • MLA:
      Garcia J, et al. “Passing the Baton: Community-Based Ethnography to Design a Randomized Clinical Trial on the Effectiveness of Oral Pre-Exposure Prophylaxis for HIV Prevention among Black Men Who Have Sex with Men.” Contemporary Clinical Trials, vol. 45, no. Pt B, Jan. 2015, pp. 244–251. EBSCOhost, doi:10.1016/j.cct.2015.10.005.
    • Chicago/Turabian: Humanities:
      Garcia J, Colson PW, Parker C, and Hirsch JS. “Passing the Baton: Community-Based Ethnography to Design a Randomized Clinical Trial on the Effectiveness of Oral Pre-Exposure Prophylaxis for HIV Prevention among Black Men Who Have Sex with Men.” Contemporary Clinical Trials 45, no. Pt B (January 1, 2015): 244–51. doi:10.1016/j.cct.2015.10.005.
    • Vancouver/ICMJE:
      Garcia J, Colson PW, Parker C, Hirsch JS. Passing the baton: community-based ethnography to design a randomized clinical trial on the effectiveness of oral pre-exposure prophylaxis for HIV prevention among Black men who have sex with men. Contemporary clinical trials [Internet]. 2015 Jan 1 [cited 2020 Aug 9];45(Pt B):244–51. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=cgh&AN=CN-01104795